Anti-SARS spike glycoprotein S1 Polyclonal Antibody
E2;E2 glycoprotein;Human coronavirus spike glycoprotein;Peplomer protein;S;S glycoprotein;SPIKE_CVHSA;Severe acute respiratory syndrome spike glycoprotein;Severe acute respiratory syndrome virus spike glycoprotein;Spike glycoprotein;VGL2. SARS-CoV
ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. ICC 1:100-500. IF 1:100-500
Store at -20°C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.03% sodium azide, 50% glycerol, pH7.4.
KLH conjugated synthetic peptide derived from SARS spike glycoprotein:101-200/1255
S1 attaches the virion to the cell membrane by interacting with human ACE2 and CLEC4M/DC-SIGNR, initiating the infection. Binding to the receptor and internalization of the virus into the endosomes of the host cell probably induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.